Mushrooms as a Resource for Mibyou-Care Functional Food; The Role of Basidiomycetes-X (Shirayukidake) and Its Major Components

Mibyou has been defined in traditional oriental medicine as a certain physiological condition whereby an individual is not ill but healthy; it also often referred to sub-healthy condition. In society focused on longevity, “Mibyou-care” becomes of primary importance for healthy lifespan expenditure. Functional foods can play crucial roles Mibyou-care; thus, the search novel resources functional food important and attractive research field. Mushrooms are target such studies because their wide variety biological functions, immune modulation anti-obesity anticancer activities, addition nutritional importance. Basidiomycetes-X (BDM-X; Shirayukidake Japanese) mushroom which several beneficial health functions. A metabolome analysis revealed more than 470 components both interest BDM-X. Further isolation purification its using radical scavenging activity UV absorbance identified ergosterol, (10E,12Z)-octadeca-10,12-dienoic acid (CLA), 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one (DDMP), formyl pyrrole analogues (FPA), including 4-[2-foemyl-5-(hydroxymethyl)-1H-pyrrole-1-yl] butanamide (FPAII), adenosine uridine major components. Biological activities attributed these were related observed functions BDM-X, suggest that this useful resource Mibyou-care medicines.